Application forms may also be obtained online as Adobe
documents at our University
of Kansas Graduate Studies web page. Once at the Graduate Studies web
page, scroll down the selections listed under the second shortcut (Getting
into the Graduate School (Incl. Application Forms) and GO to
the appropriate Application for Admission of either US Students or International
Students.
FINANCIAL SUPPORT
Most students receive financial support immediately upon admission
to the Department of Pharmaceutical Chemistry, usually in the form of a
research assistantship. No special application for financial
support is required. The competitive stipend provided ensures
that students are able to concentrate fully on their studies and research.
Students with particularly outstanding undergraduate records may be
eligible for a number of special awards. The Department of Pharmaceutical
Chemistry has been named as a Madison and Lila Self Graduate Fellowship
Program Partner at The University of Kansas. The Self-Fellowship
program provides stipend and tuition to outstanding students for
four years of graduate study. Other university-level awards include
the Honors Fellowship, awarded on a competitive basis to incoming graduate
students throughout the university, the Dissertation Fellowship, awarded
to outstanding students during their last year of doctoral study, and the
Graduate Minority Opportunity Fund Fellowship, awarded to outstanding ethnic
minority students for work towards the doctoral degree. At the department
level, the Takeru Higuchi and the Siegfried Lindenbaum Fellowships are
awarded each year to incoming graduate students with high promise.
In addition, graduate students in the department have competed successfully
for a number of external fellowships, including National Science Foundation
(NSF), American Foundation for Pharmaceutical Education (AFPE), Pharmaceutical
Research and Manufacturers' Association (PhRMA), Parenteral Drug Association
(PDA), and United States Pharmacopeia (USP) Fellowships. Additional
application materials must be supplied for many of these awards; interested
students should contact the graduate studies adviser in the department
for more information.
THE PH.D. DEGREE IN PHARMACEUTICAL CHEMISTRY
The requirements for the M.S. and Ph.D. degrees cannot be expressed
in terms of a given number of credits, the completion of a series of courses,
or the achievement of a minimum grade point average. The objective
of the program is to achieve a level of competence in those areas deemed
important in the broad area of pharmaceutical chemistry. However,
reaching this objective is clearly related to having a sound background
upon entering the program, successfully completing key graduate level courses,
and demonstrating an ability to conduct original laboratory-based research.
Entering Background
It is an expectation that entering students have competence in mathematics
that is equivalent to having completed the standard sequence in calculus
plus elementary differential equations, a course in physical chemistry
emphasizing thermodynamics and an introductory course in pharmacokinetics.
Expected Background in Chemistry, Mathematics and Pharmacy
or Their Equivalent
MATH 320 Elementary Differential Equations
CHEM 640 Biological Physical Chemistry
or
CHEM 646 Physical Chemistry I
PHCH 625 Pharmacokinetics
Further, it is highly recommended that most students take the following
courses to adequately prepare for the comprehensive examination. In all
cases, if a student has successfully completed (grade B or better) an equivalent
course at another institution, it is not necessary to repeat that course.
Chemistry Courses
CHEM 740 Principles of Organic Reactions
CHEM 742 Physical Organic Chemistry I
Pharmaceutical Chemistry Courses
PHCH 801 Issues of Scientific Integrity
PHCH 862 Pharmaceutical Equilibria
PHCH 864 Pharmaceutical Analysis
PHCH 866 Pharmaceutical Mass Transport
PHCH 972 Mechanisms of Drug Deterioration and Stabilization
PHCH 976 Advanced Topics in Biopharmaceutics and Pharmacokinetics
One of the Following
PHCH 865 Pharmaceutical Analysis II
PHCH 870 Pharmaceutical Biotechnology
Non-Required Special Interest Coursework
While not required, depending on individual interests, there are numerous
courses available from several departments that are open to Pharmaceutical
Chemistry Graduate Students at The University of Kansas (For students appointed
as Fellows on one of the NIH funded training grants, please refer to the
appropriate training grant brochure or the training program director for
clarification as to any additional requirements). The following group represents
a partial sampling of such special interest courses that have been taken
by students in recent years. It is suggested that such additional
coursework be selected by consultation with the students research mentor
and/or dissertation committee.
BIOL 672 Gene Expression
BIOL 688 The Molecular Biology of Cancer
BIOL 702 Laboratory Practice Radiation Safety Procedures
BIOL 703 Radioisotopes in Radiation Safety in Research
BIOL 718 Laboratory in Molecular Biology
BIOL 918 Physical Biochemistry
CHEM 711 Applied Electronics for Scientists
CHEM 959 Bioanalytical Chemistry
CHEM 966 Physical Organic Chemistry II
MDCH 861 Drug Metabolism
Pre-Comprehensive Bi-Annual Reviews
Student performance is initially monitored by a bi-annual review process.
Progress in coursework is reviewed and the student has the opportunity
to present a summary of their research progress to the faculty. Feedback
as regards satisfactory or unsatisfactory progress, in either coursework
or research efforts, along with future expectations are provided to the
student in a timely fashion. Typically, after two to two and one-half
academic years, the majority of students have demonstrated sufficient progress
in diadactic and experimental work to be eligible to undertake the comprehensive
written and oral exams. Current policy is that all students must
be eligible to undertake the comprehensive exams after three years (three
fall and spring semesters) or they will be asked to terminate the program.
FLORS Requirements
Before a student may take the comprehensive written and oral examinations,
he or she must complete the FLORS (foreign language or research skill)
requirement. This may be fulfilled by the demonstration of competence
in a foreign language in which there is a substantial body of scientific
literature or by successfully completing an acceptable skills development
course. Research skills in biometry (BIOL 841), radioactive material
handling (BIOL 702, 703), computer programming (C&PE 121), electronics
for scientists (CHEM 711), drug metabolism (MDCH 861), cell culture techniques
(BIOL 756), gene expression (BIOL 672), molecular biology of cancer (BIOL
688), laboratory in molecular biology (BIOL 718), drug metabolism (MDCH
861), pharmaceutical analysis II (PHCH 865), animal methods (BIOL 704),
and the writing and defense of an original research proposal (PHCH 974)
may all fulfill the research skills requirement.
The Comprehensive Examination
After satisfying course work and demonstrating suitable research skills,
the student is eligible to undertake the preliminary qualifying examination.
This process evaluates the student's background in the basic biological,
chemical and physical sciences that are central to successful research
in pharmaceutical chemistry. The examination is a two-part process,
a written examination followed by an oral exam. The subject matter
covered by the written exam is largely derived, but not limited to, the
departmental courses, seminar presentations and the student's research
experience. The oral examination usually follows the written exam
within 3-5 days. This exam allows the committee to explore with the
student any areas of apparent weakness revealed the written exam, and to
review the adequacy of performance in coursework, research and seminars.
After successfully completing the written and oral exams, the student is
qualified as a Ph.D. candidate.
Seminar Requirements
All graduate students are required to attend the weekly departmental
seminar. Seminars consist of presentations by guest speakers, faculty
members, and students. After one year of residence, graduate students
are called upon to present seminars on a regular basis. The seminar
may be based on progress achieved in their research or on a literature
review of work related to their research.
The Ph.D. Dissertation
Prior to the end of the first semester of graduate studies, each student
must choose a faculty research advisor. The advisor, in conjunction
with the student selects a dissertation research project, follows the student's
progress in coursework and research, and chairs the student's comprehensive
oral examination committee and dissertation defense committee. Each
Ph.D. candidate is required to submit and defend a dissertation resulting
from research of sufficient originality and quality for publication in
peer reviewed scientific journals. These investigations are conducted
under the supervision and guidance of the faculty adviser, with input from
the dissertation committee as needed, and normally require from 18 to 24
months of sustained effort. A minimum of three academic years in
residence is required for the Ph.D. degree.
THE M.S. DEGREE IN PHARMACEUTICAL CHEMISTRY
Except under unusual circumstances, the Department of Pharmaceutical
Chemistry does not recruit students seeking the M.S. degree. However,
all students who pass the comprehensive written and oral examinations for
the Ph.D. degree receive a non-thesis M.S. degree. Students enrolled
in the Ph.D. program who wish to terminate with the M.S. degree must satisfactorily
complete at least one third of the courses recommended for the Ph.D. degree,
present a thesis based on original research or a suitable technical report
based on the review of published research in a particular area, and pass
a final oral general examination.
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